Publikasjoner
NIBIOs ansatte publiserer flere hundre vitenskapelige artikler og forskningsrapporter hvert år. Her finner du referanser og lenker til publikasjoner og andre forsknings- og formidlingsaktiviteter. Samlingen oppdateres løpende med både nytt og historisk materiale. For mer informasjon om NIBIOs publikasjoner, besøk NIBIOs bibliotek.
2021
Sammendrag
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Forfattere
Caroline Chylinski Sokratis Ptochos Berit Marie Blomstrand Håvard Steinshamn Inga Marie Aasen Karl-christian Mahnert Stig Milan Thamsborg Spiridoula AthanasiadouSammendrag
Subclinical parasite infections in livestock production have huge economic impact on the farming industry, leading to decreased animal welfare and reduction in meat, milk and wool production. The global spread of anthelmintic resistance has exacerbated the threat of gastrointestinal nematode (GIN) infections to small ruminant health and production. Phytochemicals, such as condensed tannins (CT), have shown promising anthelmintic potential, and could complement other management practices to reduce anthelmintic use for parasite control. Conifer bark is a rich source of CT. Studies have shown that the content of CTs in Norway spruce and Scots pine varies, but on average they contain around 4% CTs. This study explored the anthelmintic activity of bark from Norwegian conifers over two seasons, extracted with three different solvents (water, acetone, methanol), against two sheep GIN, Teladorsagia circumcincta and Trichostrongylus colbriformis. Bark extracts were analysed to determine their total CT content and tested in vitro, with the aim to quantify their impact on egg hatching and L3 larval motility. Results show significant variation in efficacy of the extracts on egg hatching in a dose dependent manner. The CT content of the bark extracts were not always associated with LD50 values, indicating that other plant compounds may have additional anthelmintic effects. Preliminary results of the L3 larval motility test showed that incubation in the bark extracts had a smaller impact on this parasite stage at the concentrations tested. This research brings new insights into the potential anthelmintic activity of different phytochemicals and discusses the potential of bark extracts as a tool in the sustainable control of GIN in small ruminants.
Sammendrag
Water consumption along value chains of goods and services has increased globally and led to increased attention on water footprinting. Most global water consumption is accounted for by evaporation (E), which is connected via bridges of atmospheric moisture transport to other regions on Earth. However, the resultant source–receptor relationships between different drainage basins have not yet been considered in water footprinting. Based on a previously developed data set on the fate of land evaporation, we aim to close this gap by using comprehensive information on evaporation recycling in water footprinting for the first time. By considering both basin internal evaporation recycling (BIER; >5% in 2% of the world’s basins) and basin external evaporation recycling (BEER; >50% in 37% of the world’s basins), we were able to use three types of water inventories (basin internal, basin external, and transboundary inventories), which imply different evaluation perspectives in water footprinting. Drawing on recently developed impact assessment methods, we produced characterization models for assessing the impacts of blue and green water evaporation on blue water availability for all evaluation perspectives. The results show that the negative effects of evaporation in the originating basins are counteracted (and partly overcompensated) by the positive effects of reprecipitation in receiving basins. By aggregating them, combined net impacts can be determined. While we argue that these offset results should not be used as a standalone evaluation, the water footprint community should consider atmospheric moisture recycling in future standards and guidelines.
Forfattere
Jo Jorem AarsethSammendrag
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Sammendrag
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Forfattere
Qianwen Ding Zhen Zhang Yu Li Hongliang Liu Qiang Hao Yalin Yang Einar Ringø Rolf Erik Olsen Jihong Liu Clarke Chao Ran Zhigang ZhouSammendrag
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Forfattere
Michal Sposob Radziah Wahid Keno FischerSammendrag
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Sammendrag
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Sammendrag
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Forfattere
Klaus. R Westphal Simone Bachleitner Manja M. Severinsen Mathias L. Brundtø Frederik T. Hansen Trine Sørensen Rasmus D. Wollenberg Erik Lysøe Lena Studt Jens L. Sørensen Teis E. Sondergaard Reinhard WimmerSammendrag
The plant pathogenic fungus Fusarium graminearum is known to produce a wide array of secondary metabolites during plant infection. This includes several nonribosomal peptides. Recently, the fusaoctaxin (NRPS5/9) and gramilin (NRPS8) gene clusters were shown to be induced by host interactions. To widen our understanding of this important pathogen, we investigated the involvement of the NRPS4 gene cluster during infection and oxidative and osmotic stress. Overexpression of NRPS4 led to the discovery of a new cyclic hexapeptide, fusahexin (1), with the amino acid sequence cyclo-(d-Ala-l-Leu-d-allo-Thr-l-Pro-d-Leu-l-Leu). The structural analyses revealed an unusual ether bond between a proline Cδ to Cβ of the preceding threonine resulting in an oxazine ring system. The comparative genomic analyses showed that the small gene cluster only encodes an ABC transporter in addition to the five-module nonribosomal peptide synthetase (NRPS). Based on the structure of fusahexin and the domain architecture of NRPS4, we propose a biosynthetic model in which the terminal module is used to incorporate two leucine units. So far, iterative use of NRPS modules has primarily been described for siderophore synthetases, which makes NRPS4 a rare example of a fungal nonsiderophore NRPS with distinct iterative module usage.