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Publications

NIBIOs employees contribute to several hundred scientific articles and research reports every year. You can browse or search in our collection which contains references and links to these publications as well as other research and dissemination activities. The collection is continously updated with new and historical material.

2011

Abstract

In forest soils, saprotrophic, necrotrophic and ectomycorrhizal fungi are involved in carbon cycling. Heterobasidion annosum, white rot necrotrophic fungi, is known to decompose wood lignocellulose by secreting a broad range of oxidative enzymes. The genome H. annosum s.l. was sequenced by JGI to a 8.23X coverage and assembled into 39 scaffolds with a total size of 33.7 Mb covering more than 98% of the whole genome. Based on the genome sequence we have characterized gene families coding for enzymes known to participate in conversion of wood lignin: multicopper oxidases (MCOs, 18 genes) as laccases (Lcc), class II peroxidases (8 genes) as manganese peroxidases (MnP), glyoxal oxidases (5 genes, GLOX), quinone-reducing oxidoreductases (19 genes, QOR) and GMC oxidoreductases (12 genes) as aryl alcohol oxidases (AAO). We studied the genomic organisation and phylogeny of these genes as well as their expression using qRT-PCR. Comparative and phylogenetic analyses of genes coding for enzymes involved in wood lignin conversion and decomposition (i.e. lignin-modifying class II peroxidases) reveal differences between white- and brown-rot, necrotrophic and saprotrophic wood-decaying basidiomycetes. Transcript profiling using qRT-PCR revealed that some transcripts were very abundant in lignin-rich media, in cellulose-rich media, in wood or in the free-living mycelium grown liquid culture, suggesting specific functions of these genes, which need to be studied further.