Publications
NIBIOs employees contribute to several hundred scientific articles and research reports every year. You can browse or search in our collection which contains references and links to these publications as well as other research and dissemination activities. The collection is continously updated with new and historical material.
2024
Authors
Xiao-Yan Ma Jin-Wei Li Qing Li Zi-Han Yan Xi Cheng Min-Rui Wang Zhibo Hamborg Lu Bao Dong Zhang Min-Ji LiAbstract
No abstract has been registered
Authors
Marta Vergarechea Clara Antón Fernandéz Jane Uhd Jepsen Ole Petter Laksforsmo Vindstad Rasmus AstrupAbstract
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Authors
Andrea Seldeslachts Marius Filomeno Maurstad Jan Philip Øyen Eivind Andreas Baste Undheim Steve Peigneur Jan TytgatAbstract
Lepidopterism, a skin inflammation condition caused by direct or airborne exposure to irritating hairs (setae) from processionary caterpillars, is becoming a significant public health concern. Recent outbreaks of the oak processionary caterpillar (Thaumetopoea processionea) have caused noteworthy health and economic consequences, with a rising frequency expected in the future, exacerbated by global warming promoting the survival of the caterpillar. Current medical treatments focus on symptom relief due to the lack of an effective therapy. While the source is known, understanding the precise causes of symptoms remain incomplete understood. In this study, we employed an advanced method to extract venom from the setae and identify the venom components through high-quality de novo transcriptomics, venom proteomics, and bioinformatic analysis. A total of 171 venom components were identified, including allergens, odorant binding proteins, small peptides, enzymes, enzyme inhibitors, and chitin biosynthesis products, potentially responsible for inflammatory and allergic reactions. This work presents the first comprehensive proteotranscriptomic database of T. processionea, contributing to understanding the complexity of lepidopterism. Furthermore, these findings hold promise for advancing therapeutic approaches to mitigate the global health impact of T. processionea and related caterpillars.
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Authors
Mohammad Tirgariseraji A. Pouyan Nejadhashemi Yaghoob Jafari Tomas Persson Mahmood Sabouhi Sabouni Alisher Mirzabaev Alireza Nikouei Naser Shahnoushi FroshaniAbstract
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Authors
Nina SvartedalAbstract
No abstract has been registered